The molecular mechanism of sex hormones on Sertoli cell development and proliferation
… and testosterone signaling pathways in Sertoli cell proliferation… process, for example 5α-dihydrotestosterone
(DHT) regulates … cell cycle arrest by interacting with 17β-estradiol (E2) (106). …
(DHT) regulates … cell cycle arrest by interacting with 17β-estradiol (E2) (106). …
Follicle-stimulating hormone signaling in Sertoli cells: a licence to the early stages of spermatogenesis
JM Wang, ZF Li, WX Yang, FQ Tan - Reproductive Biology and …, 2022 - Springer
… The cAMP/PKA signaling pathway participates in Sertoli cell differentiation, SSC self-renewal …
in immature rat SCs activates the caspase 9 mediated intrinsic apoptotic pathway [118]. …
in immature rat SCs activates the caspase 9 mediated intrinsic apoptotic pathway [118]. …
Sex hormones regulate lipid metabolism in adult Sertoli cells: A genome-wide study of estrogen and androgen receptor binding sites
… by estrogen (A) and androgen (B) after 17β-estradiol (E2) (10 −9 M… These apoptotic bodies
are phagocytosed by Sertoli cells. … In addition, estrogen also activates signaling pathways via …
are phagocytosed by Sertoli cells. … In addition, estrogen also activates signaling pathways via …
Dimethylbisphenol A inhibits the differentiation of stem Leydig cells in adult male rats by androgen receptor (NR3C4) antagonism
L Shi, J Li, F Tian, Y Tang, S Wang, Q Li, Y Zhu, Q Zhu… - Toxicology Letters, 2022 - Elsevier
… , Sod2, Cat, and Gpx1), apoptosis-related genes (Bcl2 and Bax), … regulated NR3C4 expression
in Sertoli cells and immature … Leydig cell maturation, other signaling pathways may be …
in Sertoli cells and immature … Leydig cell maturation, other signaling pathways may be …
[HTML][HTML] Effects of Pgam1-mediated glycolysis pathway in Sertoli cells on Spermatogonial stem cells based on transcriptomics and energy metabolomics
X An, Q Li, N Chen, T Li, H Wang, M Su… - Frontiers in Veterinary …, 2022 - frontiersin.org
… to jointly regulate the proliferation and apoptosis of SSCs (13)… the testis by insulin and IGF-I
in rats (22). When PI3K-specific … Akt signaling pathway, MAPK signaling pathway, metabolism …
in rats (22). When PI3K-specific … Akt signaling pathway, MAPK signaling pathway, metabolism …
Impact of endocrine-disrupting chemicals on steroidogenesis and consequences on testicular function
C Walker, S Garza, V Papadopoulos, M Culty - Molecular and Cellular …, 2021 - Elsevier
… stem cells receive regulatory signals not only from Sertoli cells … In the same study, 17β-estradiol
was also found to activate … disrupting signaling pathways and cellular communications. …
was also found to activate … disrupting signaling pathways and cellular communications. …
[HTML][HTML] Impacts of immunometabolism on male reproduction
L Ye, W Huang, S Liu, S Cai, L Hong, W Xiao… - Frontiers in …, 2021 - frontiersin.org
… Metabolism, as well as the key signaling pathway mediating metabolic activity in various …
also regulate Sertoli cell metabolism. 5α-Dihydrotestosterone and 17β-estradiol are reported to …
also regulate Sertoli cell metabolism. 5α-Dihydrotestosterone and 17β-estradiol are reported to …
Direct actions of adiponectin on changes in reproductive, metabolic, and anti-oxidative enzymes status in the testis of adult mice
… Schematic illustration of adiponectin signal transduction pathway implicating a … insulin
signaling pathway in the regulation of Sertoli cells and germ cells proliferation, survival, apoptosis, …
signaling pathway in the regulation of Sertoli cells and germ cells proliferation, survival, apoptosis, …
Androgen signaling in male fishes: Examples of anti-androgenic chemicals that cause reproductive disorders
M Golshan, SMH Alavi - Theriogenology, 2019 - Elsevier
… and does not convert to 17β-estradiol. However, circulatory levels … its 5α-reduced derivative
(5α-dihydrotestosterone (DHT)) are … 11-KT activates the Sertoli cells to produce Activin B that …
(5α-dihydrotestosterone (DHT)) are … 11-KT activates the Sertoli cells to produce Activin B that …
Physiology of Testicular Function
J Wistuba, N Neuhaus, E Nieschlag - Andrology: Male Reproductive …, 2023 - Springer
… by immature, not yet terminally differentiated Sertoli cells and … Sertoli cells, the apoptosis of
spermatocytes, spermatids and … converted into 17β-estradiol and 5α-dihydrotestosterone (DHT…
spermatocytes, spermatids and … converted into 17β-estradiol and 5α-dihydrotestosterone (DHT…